| RRRC:0392 | Strain Name: LEW-RT1.Bm1Trg | Common Name: RT1.B | |||
| Donor | Joel Taurog, UTSW Med Center | ||||
| Genetic Description | |||||
| Genotypes Available |
Heterozygous/Hemizygous |
Homozygous
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Wild Type
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Transgene Positive |
Transgene Negative
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Transgene Other
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| Coat Color | WHITE | ||||
| Disposition Status |
Embryo
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Sperm
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Live Animals
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Other
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| Genetic Status |
Inbred
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Segregating
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Congenic
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Consomic
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Induced Mutation
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Coisogenic
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Transgene
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Recombinant
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Outbred
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Spontaneous Mutation
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Transposon Mutation
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Other
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| Research Category |
Diabetes/Obesity
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Cardio/Hypertension
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Neurobiology
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Onocology
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Metabolism
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Osteosis
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Ophthalmology
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Otorhinology
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Dentistry
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Internal Organ
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Dermatology
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Immunology
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Reproduction
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Hematology
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Behavior
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Infectious
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Urology
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Pharmacology
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Development
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Reporter Gene
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Transplantation
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Alcoholism
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Others
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| Strain Characteristics | ENU induced mutation in a Sprague Dawley rat resulting in a phenotypic change at the RT1.B MHC locus such that antibody binding to the RT1.B locus is no longer present. Animals carrying this mutation fail to have OX-6 antibody binding to the RT1.B locus. The exact nature of the mutation has not been genetically characterized. Mutation was backcrossed onto the Lewis strain. | ||||
| Research Applications | Immunology and transplantation | ||||
| Breeding Conditions | random intra-strain | ||||
| Genotyping | |||||
